Drug resistance is one of the main hurdles for the black rose globe successful treatment of breast cancer.The synchronous targeting of apoptosis resistance and survival signal transduction pathways may be a promising approach to overcome drug resistance.In this study, we determined that evodiamine (EVO), a major constituent of the Chinese herbal me
The Status of the Implementation of the Building Information Modeling Mandate in Poland: A Literature Review
BIM is being strongly implemented in design companies.General contractors are using it during investment projects, and boards are using it for the maintenance and operation of buildings or infrastructure.Without the so-called BIM mandate (mandatory in public procurement), this is hard to imagine, even though it has already been implemented in many
Feasibility and Safety of Perioperative Chemotherapy With Fluorouracil Plus Leucovorin, Oxaliplatin, and Docetaxel for Locally Advanced Gastric Cancer Patients in China
BackgroundNeoadjuvant fluorouracil plus leucovorin, oxaliplatin, and docetaxel (FLOT) has shown significant benefits for gastric cancer patients.However, it has not been well accepted in Asian countries.We conducted a prospective study on the safety and feasibility of the FLOT regimen in Chinese patients.MethodsPatients with adenocarcinoma of the s
Analysis of entrepreneurial readiness of family welfare education study program students concentrating in culinary arts
Research on student readiness for entrepreneurship is very important to understand how to enter the business world better.This sm-x610nzaaxar study aims to describe the entrepreneurial readiness of students of the Family Welfare Education Study Program specializing in Culinary Arts at Syiah Kuala University.This type of research is descriptive quan
Systemic and local immune responses to intraocular AAV vector administration in non-human primates
Positive clinical outcomes in adeno-associated virus (AAV)-mediated retinal gene therapy have often been attributed to the low st albans alpaca scarf immunogenicity of AAVs and immune privilege of the eye.However, several recent studies have shown potential for inflammatory responses.The current understanding of the factors contributing to inflamma